Contents

• Introduction 
• New to the guidelines 
• Before you begin 
• Assessment of the risk of HIV transmission
  
  1. What is the HIV transmission risk/exposure?
  2. What is the HIV status of the source individual? 
  3. What is the HIV status of the exposed individual? 
• When to Prescribe PEP 
  • PEP recommendations after occupational exposure 
• Immediate management of an individual with known or suspected exposure to HIV 
• Clinical assessment and follow-up 
• Laboratory assessment and follow-up 
• Prescribing PEP 
  • Recommended PEP regimens 
  • Medications and cautions
• Management of possible exposure to other conditions
  
  1. Hepatitis B 
  2. Sexually transmissible infections 
  3. Hepatitis C 
  4. Pregnancy and breastfeeding 
  5. Tetanus
• Additional clinical management issues
  
  1. Preventive behaviours while being managed for HIV exposure 
  2. Individuals at risk of HIV acquisition who decline PEP
  3. Individuals at negligible risk of HIV transmission who request PEP 
  4. Individuals who re-present for NPEP 
  5. Individuals who are on PrEP 
  6. Transitioning from PEP to PrEP 
  7. Renal disease 
  8. Gender identity and history 
  9. Individuals who have been sexually assaulted 
  10. Children 
  11. Prisoners and detainees 
  12. Individuals who commenced PEP overseas
  13. Risk communication: understanding the risk of exposure 
• References 
• Information for clinicians 
• Information for patients
• Appendix 1: Drugs commonly prescribed in PEP regimens  

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